With the addition of the information-rich TQ Detector, LaChromUltra® U-HPLC system further solidifies its position as the leader in chromatographic analysis for a wide range of applications.
The LaChromUltra® U-HPLC system, in combination with the TQ Detector, provides unmatched quantitative analysis and characterization capabilities.
Seamless integration of the U-HPLC system and the TQ Detector with Empower™ 2 control.
Performs SIR, MRM, Product, Precursor, and Neutral Loss Scans on the U-HPLC timescale.
Equipped with dual ESI/APCI source as standard, with optional APPI available.
20 ms polarity switching.
The TQ Detector
The Waters® TQ Detector is a compact, benchtop tandem quadrupole API mass spectrometer. The system features new automated setup technology and fast acquisition capability for simple, rapid LC/MS/MS. The following items are included as part of the standard system:
ZSpray™ API INTERFACE
Atmospheric pressure ionization (API) LC interface including: one easily dismountable ion source enclosure, cone gas facility for chemical noise reduction, electronic mass flow meters for drying gas and cone gas, tool free cone removal, source isolation valve, and micrometer probe positioning. The source and spraying elements are visible through a transparent enclosure and are easily accessible via a quick-release door.
TANDEM QUADRUPOLE ANALYZfER
2x High performance quadrupole analyzers with inter-element beam focusing and a mass range of 2-2000 amu. Pre-filters maximize resolution and transmission especially at high mass and also to eliminate main filter cleaning. All lens and analyzer voltages are digitally controlled and recorded. Analyzer parameters may be programmed with respect to mass for optimal performance.
T-WAVE™ COLLISION CELL
High-efficiency gas cell for collision induced dissociation. Programmable software controls collision energy and gas pressure, including experimental record. The Travelling Wave (T-Wave™) device enables rapid cell clearance and refill for fast MRM transition switching while maintaining optimum signal to noise.
VACUUM SYSTEM
Clean, differentially pumped, automated vacuum system, comprising of air-cooled Pfeiffer splitflow turbomolecular drag pump evacuating both the source & analyzer, vacuum read backs and system vent/pump cycles that are digitally monitored and controlled to provide total software control and ensure fail-safe operation in the event of power failure, and one Leybold rotary pump for backing of the turbo pump (to be ordered separately).
DETECTOR
Dynolite photomultiplier detector. A High-voltage conversion dynode and phosphor are positioned at 90° off-axis to the analyzer for the elimination of neutral noise. The photomultiplier is enclosed in its own vacuum envelope for long life. The detector operates in both positive and negative ion modes, and can switch rapidly under software digital control.
*LaChromUltra is a registered trademark of Hitachi High Technologies America, Inc. Waters, Empower, T-Wave, and ZSpray are trademarks of Waters Corporation.
Integrated sample/calibrant delivery system and programmable divert valve
Automated mass calibration
Automated sample tuning
Automated SIR and MRM method development
LC/MS System Check—automated on-column performance test
API source
ZSpray™ dual-orthogonal source for robust sampling
Vacuum isolation valve
Tool-free sampling cone removal
Plug-and-play probes
De-clustering cone gas
Software control of all gas flows
Ionization modes
Electrospray—included as standard
ESCi multimode ionization—included as standard
IonSABRE™ APCI—option
Dual APCI/APPI—option
Ion source transfer optics
High-efficiency hexapole ion guide
Mass analyzer
Two high-resolution quadrupole analyzers (MS1/MS2), plus pre-filters to maximize resolution and transmission while preventing contamination of the main analyzers.
Collision cell
T-Wave™ collision cell for optimum ion transfer and confinement, allowing fast MS/MS acquisition
Software-programmable gas flow
Detector
Low noise, off axis, long life photomultiplier detector
Digital dynamic range up to 4 x 106
Vacuum system
Single, split flow air-cooled Pfeiffer vacuum turbomolecular pump evacuating the source and analyzer
One Leybold Sogevac SV4OBI rotary backing pump
Software
System control via Empower™ 2
Regulartory approvals
IVD, NRTL, and CE
*It should be noted that the above are not standard installation specifications. All TQ detector instruments will be installed and tested in accordance with standard performance tests. Waters, ESCi are registered trademarks of Waters Corporation. IntelliStart, Empower, IonSABRE, ZSpray, T-Wave, OpenLynx, and QuanLynx are trademarks of Waters Corporation. All other trademarks are property of their respective owners.
The information-rich TQ Detector and LaChromUltra® U-HPLC system create a perfect combination for simple, fast, and sensitive detection of HPLC analytes.
